Autism is a complex neurodevelopmental disorder that usually presents in eary childhood. It is usually first noticed between the ages of 1 1/2 to 3 years as a regression of developmental gains noted from birth to age 1 1/2. It is 6 times more likely to appear in boys than girls.

The apparent increase in the diagnosis of autistic spectrum disorders from 4-5 in 10,000 children in the 1980's to 30-60 in 10,000 children in the 1990's, and 1 in 166 children in 2006 has raised great concern. The ratio is worse for boys. 1 in 80. This increased prevalence of autism has enormous future family and public health implications and has stimulated intense research into potential etiologic factors.

Abnormal folate metabolism and low glutathione concentrations have been reported in the following neurological disorders: Autism, Alzheimer's disease, Parkinson disease, schizophrenia, and Down syndrome. I believe this is primarily the result of exposure to mercury and aluminum. Mercury and aluminum block methionine methylation and transsulfuration metabolites, which are very important energy mechanisms in brain cells (neurons). The presence of testosterone and fluoride substances also makes the enregy problem worse.

High homocysteine is the marker for high risk of an abnormal pregnancy. It needs to be in the normal range to reduce risk of harm to the baby. Women should avoid eating fish, visiting the dentist, and should NOT receive RhoGam during pregnancy unless it is free of aluminum and thiomerisol (mercury).

When a woman discovers she is pregnant, she should take 1.2 mg folate and 50 mg B6 daily plus 1,000 mcg Methyl B-12 by subcutaneous injection twice weekly to normalize homocysteine levels. She should also take 1,000 mg of Betaine daily. These can also be supplemented by Choline. This should decrease the change of having an autistic or Down syndrome child. Do not allow your newborn to be injected with Hepatitis B vaccine.

The autistic child should be given 800 mcg of USP grade follinic acid and 1,000 mg of betaine (anhydrous trimethylglycine- USP twice daily, plus 1,000 mcg Methyl B-12 by subcutaneous injection twice weekly.

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